** Patient feedback of dosen taken (visual/acoustic)

Lactose carrier (taste feedback)

N/A Dose counter

Dose counter measuring inhalations actually taken

Accurate & consistent dose delivery

FPF air flow rate independence

Achievable IFR (asthmatic child, severe asthma COPD)

++++ Device resistance

? Minimum FR controlled to achieve adequate lung deposition?

N/A Overdose-secure

(1) Dose metering: blister pack (maximum)

Reservoir (maximum)

N/A Advance warning of last dose

Protection from ambient humidity

N/A Device lock.out


1 Max. number of doses

How to use Handihaler

Handihaler® Despite a high intrinsic resistance the HandiHaler® can be successfully used by patients, who are not able to generate high inspiratory flows. In clinical studies it was shown that even patients with severe airway obstruction were able to achieve the required minimal inspiratory flow rate.

With inspiratory flow rates of 20 to 60 l/min the HandiHaler® releases consistently between 55-60% of the metered dose. The fraction of particles smaller than 5.6µm ranges from 20% at an inspiratory flow of 20 l/min to 25% at a flow of 60 l/min.

Due to the high sensitivity of tiotropiumbromide to humidity the HandiHaler® has to be loaded with a single drug capsule before each use. During inhalation the capsule vibrates which can be noticed acoustically.

The Handihaler® is approved for tiotropiumbromide (Spiriva®).

This section contains a list of things you should do (DOs) and things you shouldn’t do (DON’Ts) when using the HandiHaler. This list only covers items known from practice to be the most important and most likely to be forgotten or performed incorrectly by patients; this information is in addition to the prescribing and other information provided with the HandiHaler.